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Use of live potted lemon grass for outdoor mosquito control in Tanzania
…grass. A total of 5,203 and 3,897 female Culex quinquefasciatus mosquitoes were collected at baseline and at the end of the intervention respectively, which showed a significant change in the number of mosquito bites in the houses after the intervention. After dissection, none of the captured mosquitos had filarial worms. The team would like to…
Mycobacterium tuberculosis strains carrying Arctic essential genes - a novel tool for disease diagnosis, drug discovery and vaccine development
…were introduced. This showed that the M. tuberculosis genes can functionally substitute for the E. coli genes. Establishing this system will allow the use of directed evolution to change M. tuberculosis genes into temperature-sensitive forms that can be used to engineer M. tuberculosis strains to temperature-sensitivity. The project was not completed due to time constraints, but…
Turning hope into action: Youth peer health education in rural Tanzania
…YPHE program and identified goals of implementing the program into select schools in their districts over the next five years. Teachers stated that they were going to change some of their teaching strategies to include inductive and participatory learning approaches, similar to those employed in the YPHE training program. The team intends to monitor, support…
Low-cost and portable capsule endoscopic system with novel imaging and multi-lighting vision capability
…image) storing (named WCE Logger) and image viewing and analysis (WCE Viewer). WCE Logger is used to record data and as a real-time viewer. A user can change image size, lighting modes and other parameters of the capsule pill in real-time. In the WCE Viewer, a user can review and examine the captured images offline. Both…
Diagnosing fevers better: Improving diagnosis of febrile illnesses by uniting disease ecology and satellite imagery
…or negative) were related to the amount of An. arabiensis habitat in a two-kilometer neighborhood. The resulting patterns of malaria risk and, in particular, the pattern of change in malaria risk pre- and post-intervention, are consistent with what researchers in the field have observed. Having demonstrated the ability of Maxent habitat maps to predict malaria…
Ultra low cost, simply operated, lab-on-a-chip detection of arsenic contamination in Bangladesh's well waters
…put the test paper into a small container of the contaminated water; then, after some time, take the paper out and the colour on the paper will change. At the moment, the limit of detection for the device is ~70 ppb, which is higher than the World Health Organization’s threshold of 10 ppb. Also, the…
A rapid low-cost test for pulmonary tuberculosis in low-income countries
…proposed using an exothermic chemical reaction to generate the three required temperatures on individual heating surfaces, and maintaining the same temperature on each heating surface using phase change materials (PCMs) as a heat sink. A spring mechanical system that would repeatedly move the sample onto each heating surface would also need to be developed, as…
My Sisters Keeper (MSK): Ending Female Genital Mutilation in South Eastern Nigeria
This project will address persisting female genital mutilation/cutting (FGM/C) practices by empowering community members to be agents of change in challenging social norms around FGM/C. Toll free telephone mental health counselling service and hospital referrals will be provided to victims and persons at risk of FGM/C.
Point-of-Care Technology for the Diagnosis of Multiple Diseases: A Solution to the Disease Overtreatment Problem
…that the positively charged microgel layer can collapse in the presence of negatively charged, single-stranded DNA (ssDNA) due to ssDNA-induced microgel crosslinking. This collapse results in a change in the etalon’s optical properties, which can be used to detect target DNA in a complex mixture. However, the team did not manage to develop the proposed…
Developing a home-based geo-information system to optimize local level interventions against malaria mosquitoes
…and anthropogenic variables across all study villages. Outcome The team successfully identified the areas where mosquitoes were either more or less abundant within the villages through observational changes, and distribution of the environmental variables and anthropogenic features. These changes were precisely and reliably recorded and updated by village community members, who can associate mosquito abundance…