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Innovation

Effect of L-type calcium channel blockers (Amlodipine) on myocardial iron deposition in thalassemic patients with moderate to severe myocardial iron deposition: A Randomized Control Trial

…an inherited blood disorder where the body makes an abnormal form of hemoglobin. The disorder results in large numbers of red blood cells being destroyed, which leads to anemia. Treatment for thalassemia often involves regular blood transfusions and folate supplements. However, regular transfusions can lead to transfusional hemosiderosis – an accumulation of excess iron within the body, including liver,…in thalassemia patients involves chelation therapy. Even in a well-treated population receiving regular blood transfusions and iron chelation therapy, up to 43% of patients were found to have significant cardiac iron overload. Literature supports that cardiac iron load-related complications may contribute up to 70% of morbidity and mortality in thalassemia patients. Therefore, new approaches to reducing this iron deposition are needed. Solution The objective of the project was to

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Innovation

ParentUp - SMS-based maternal support and Postpartum Depression screening for mothers in urban locales in the Philippines

Issue In the Philippines, 200,000 teenagers become mothers each year. The majority of these girls belong to low-income communities with poor access to mental health resources and emotional support. These issues are exacerbated by the social stigma surrounding teen pregnancies.Postpartum depression (PPD) occurs in 10-18% of women following the birth of their child. Social stigma and low health service access have culminated in a precarious situation for pregnant girls in the Philippines, as many communities do not have regularly available mental health professionals and counsellors. SolutionThe ‘ParentUp’ app aimed to provide informational and emotional support…and volunteer parents.The refined application allowed mothers to send health questions via SMS messages to local health experts. The program required a fee of 1 peso to sign up.The project had 2 phases:Research phase: Used surveys to analyze the awareness of PPD in Caloocan.Pilot phase: Gained further insights by interviewing low-income mothers in Taguig to

84
Innovation

Creating a unique repository to elevate the significance of HIV-linked cancers

…of HIV-positive adults will develop cancer and 1.6 million Kenyans currently live with HIV. Cancer ranks third as a cause of death in Kenya and contributes 7% to the total national mortality yearly, with an annual mortality rate of over 22,000. There is a low awareness of cancer and even less knowledge of the link with…of the National Cancer Act in 2012 in Kenya made cancer a notifiable disease, meaning that national and regional governments must collect and report all cancer cases, for control, management and resource allocation. Solution This project tested the viability of setting up a population-based cancer and HIV-linked registry to document cancer patterns in two counties in Kenya. A unique mobile telephony cancer–HIV-linked registry was developed to address the knowledge,…patients in the pilot counties, to obtain information regarding gaps in cancer knowledge, attitude and practices. To facilitate access to the data, a simple, web-based application was designed that is hosted on a secure server, running on a platform that imported the summarized registry data. Outcome The project resulted in the successful development of a…

84
Innovation

Medical appointment reminders and health tips delivered via voice message to new and expectant mothers who speak Quechua -- a South American language with no written component

Issue Maternal health has become a priority worldwide. Many rural communities do not get access to information on maternal health because messages are not in their local language. Solution Quechua is the language spoken in the rural Andes region of Peru and does not have a written component. To reach this population, the project used voice messages in the Quechua language to give mothers reminders for medical appointments, general pregnancy health tips and nutritional tips on how to reduce pregnancy complications. The project team started by carrying out an exploratory study, followed by…cloud-based voice system that sends voice messages to multiple users automatically. The messages contained information on the need for antenatal visits, plus the importance of ferrous sulfate supplement, tetanus vaccination and how to recognize pregnancy-related danger signs. A randomized study was then conducted to evaluate the impact of the intervention with 208 Quechua women. Outcome Results showed that the use of voice messages in Quechua…

84
Innovation

Scaling up of the BasicNeeds Mental Health and Development Model through a social franchise approach

BasicNeeds’ unique approach works with existing health and community systems, and staff to provide community based mental health treatment through outreach clinics, mental health camps and regular check-ups. However, treatment alone is not enough for sustained improvements to mental health, which is why the Model also increases an individual’s access to emotional and practical support through self-help groups, improves their capacity to

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Statement by Grand Challenges Canada

The Board of Directors of Grand Challenges Canada (GCC) announced today that GCC’s founding Chief Executive Officer, Dr. Peter A. Singer, has decided to step down from his role by June 30, 2018, or as soon as his successor is selected Toronto, Canada – On behalf of the Board of Directors, Guylaine Saucier (Chair) today…Canada, helping turn bold ideas into big impact in Canada and around the world. Throughout his tenure, Peter nurtured a deep well of talent and an exceptional group of next-generation leaders. We are enormously grateful to Peter for all his efforts and his many successes on behalf of GCC. While saddened to see Peter leave his executive leadership role, we are pleased that he has…

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Page

Website Legal Terms and Disclaimer

…AT HTTPS://GCC.FLUXX.IO (THE “COMMUNITY PORTAL”), OR ANY OTHER GRAND CHALLENGES CANADA WEB PROPERTIES OR THIRD-PARTY SITES MANAGED BY GRAND CHALLENGES CANADA (TOGETHER, THE “WEBSITE”), OR YOUR PROVISION TO GRAND CHALLENGES CANADA OF ANY CONTENT OR PERSONAL INFORMATION, CONSTITUTES YOUR ACCEPTANCE OF, AND IS CONDITIONAL UPON YOUR ACCEPTANCE OF AND COMPLIANCE WITH, THESE TERMS AND CONDITIONS, INCLUDING THE GRAND CHALLENGES CANADA PRIVACY POLICY (THE “PRIVACY POLICY”), ALL AS AMENDED FROM TIME TO TIME.…users of the Website are employees or other agents of entities, so references to “You” means both: (1) any entity or individual that is Your employer or for whom You act as agent, and (2) the user individually, unless otherwise stated on the Website or in this Agreement. “We” and “Us” means both You and…

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Canada and Global Health Innovation: Canadians are Making a Difference

In November 2011, the Canadian Academy of Health Sciences (CAHS) released its report Canadians Making a Difference.  One of the five key roles for Canada in global health that was emphasized in the report was innovation: Canada’s long-term impact on global health will be driven by our ability to develop and implement new ideas and to bring them to scale where they are needed—what is commonly called “innovation.”  The report also highlighted how innovation cuts across…September 2013. At McGill University, Nikita Pai has tested a model to ensure the acceptability of HIV oral self-testing in South Africa that has the potential to significantly improve health outcomes and save lives. This strategy increases the percentage of people who know their HIV status and thus reduces transmission rates. In addition, it saves…of Canada, will be supporting ~ 70 new Canadian innovations per year through our Stars in Global Health program and we are starting to support the scaling up of successful innovations from current grantees through larger follow-on investments.  We will support even more Canadian innovators through our targeted challenges – Saving Lives at Birth, Saving…

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The Indigenous Innovation Initiative welcomes two experienced leaders to the team

Grand Challenges Canada is excited to welcome two experienced leaders to lead the Indigenous Innovation Initiative (I3) team. Julie Williams was appointed as the Director of I3 and Kathryn Manners joined as the Deputy Director. Julie Williams, Director of the Indigenous Innovation Initiative Julie is Ojibway from Rama/Mnjikaning First Nation and is a member of…of formal institutional learning and traditional learning on the land and in storytelling. After years of studying and working abroad, she returned to Turtle Island to take up work in service to Indigenous Peoples. Holistic health and well-being for communities have been a driving factor in Julie’s career. Julie has experience working at the Wabano Centre for Aboriginal Health, where she supported the development of culturally…Public Service, along with contributing extensively in the non-profit environment. Kathy’s experience in the corporate, public, and social sectors is an invaluable asset. Kathy takes a human-centered design approach to all her work. She was the key researcher, facilitator, and author of “Voices of Lived Experience with Poverty,” a report that highlighted a strength-based approach…

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Innovation

Low cost and easy-to-use resuscitator that can be used without electric power

…immediately at birth and about 6 million require basic neonatal resuscitation. One hundred percent of patients from remote hospitals needing artificial respiration in low-income settings are transferred to hospitals with higher levels of available assistance. Patients often receive unsafe respiratory therapy during their transfer, due to a lack of proper equipment to control the air pressure that is supplied. Solution The main aim of the project was to develop a prototype for a hand-held, mechanical, neonatal resuscitator called a “Volume Adjustable Manual Resuscitator”. The prototype was developed for manual operation by professionals with little training. It was also designed to allow a physician to simultaneously conduct respiratory therapy as well as auscultation and cardiac resuscitation of the patient. The Volume Adjustable Manual Resuscitator generates a series…